Innate Immunity and Neuroinflammation

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Innate Immunity and Neuroinflammation

Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and comp...

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Innate immunity and adjuvants

Innate immunity was for a long time considered to be non-specific because the major function of this system is to digest pathogens and present antigens to the cells involved in acquired immunity. However, recent studies have shown that innate immunity is not non-specific, but is instead sufficiently specific to discriminate self from pathogens through evolutionarily conserved receptors, designa...

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Innate and acquired immunity

• The cells of the immune system are divided into lymphoid and myeloid lineages. The former include T lymphocytes and their subsets identified by CD markers, B lymphocytes and natural killer (NK) cells. The myeloid lineage includes the neutrophils, eosinophils and basophils as well as the monocyte/ macrophage series and platelets. • Innate immunity depends on physical, physiological and chemica...

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Innate immunity

From the discovery of antibodies in the late nineteenth century until very recently, the focus of most research in immunology has been the so-called adaptive immune response. Adaptive immune responses are highly specific for a given microorganism and it is the T and B lymphocytes of the adaptive immune response, and the antibodies produced by the B lymphocytes, that are responsible for lasting ...

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ژورنال

عنوان ژورنال: Mediators of Inflammation

سال: 2013

ISSN: 0962-9351,1466-1861

DOI: 10.1155/2013/342931